Salod(H), Wardha, M.S., India-442004
dattameghecollegeofpharmacy@gmail.com

Animal Facilities

Pharmacological Activities

Sr. No.
Animals Pharmacological activities
1
Albino Wistar Rats
(Rattus norvegicus)
  • Psychopharmacological studies
  • Study of analgesics and anticonvulsants
  • Bioassay of various hormones, such as insulin, oxytocin, vasopressin
  • Study of estrus cycle, mating behavior and lactation
  • Isolated tissue
  • Chronic study
  • Gastric acid secretion
  • Hepatotoxicity studies
  • Study on mast cells
2
Sprague-Dawley Rats (Rattus norvegicus)
  • Anti-diabetic study
  • Model for obesity
  • Anti-cancer Activity
  • Used in cardiovascular diseases
3
Swiss Mice
(Mus musculus)
  • Toxicological studies
  • Teratogenicity studies
  • Bioassay of insulin screening of analgesic and anticonvulsant
  • Screening of chemotherapeutic agents
  • Studies related to genetics and cancer research
  • Drugs action on CNV
  • Swiss albino mice are commonly used species
  • Other strains are – Balb C and C-57
4
Balb C and C-57 Mice
  • Oncology Study
  • Anti-inflammatory Study
  • Used in autoimmunity
5
Guinea Pig
(Cavia Porcellus)
  • Evaluation of bronchodilators
  • Anaphylactic and immunological studies
  • Study of histamine and antihistamines
  • bioassay of digitalis
  • Evaluation of local anaesthetics
  • Hearing experiments because of sensitive cochlea
  • Isolated tissues especially ileum, heart
  • Study on TB and ascorbic acid metabolism
6
Rabbits
(Lupas Cuniculus)
  • Pyrogen testing
  • Bioassay of anti-diabetic, curareform drugs and sex hormones
  • Screening of agents affecting capillary permeability
  • Drugs used in glaucoma
  • Pharmacokinetic studies
  • Studies related to antifertility agents
  • Isolated preparations like heart, duodenum, ileum, pre's
  • Study on local anesthetics
  • Study on miotic and mydratics
7
New Zealand rabbits (Oryctolagus cuniculus)
  • Toxicity Study
  • Safety testing
  • Implantation of medical devices

List of Instruments

Sr. No.

Instruments/ Equipments

Experimental use

1
HPTLC

  • Sample Detection
  • Separation
  • Sample application
  • Drug degradation
2
Atomic Absorption

  • Detection of metals
  • Diagnosis of electrical injury in rats
3
Plethysmometer
  • To evaluate the inflammatory response
4
Biological Projection Microscope (Magnus)
  • To observe cells, tissues, and other biological specimens
  • To view the microbial world
  • Performing sample imaging
  • Discovery of cells
5
Auto analyser
  • To measure different chemicals and other characteristics in a number of biological samples
  • Mechanization and automation.
6
Spectrophotometer
  • To quantitate the amount of a chromogen produced in a chemical reaction between an analyte in a clinical sample and the reagents
  • Development of better analytical procedures and quality.
  • Colour measurement in a variety of applications.
7
Electrophoresis Instruments
  • Compare DNA
  • Genetic testing
8
Tissue Homogenizer RQ (127-A, Remi)
  • Designed for homogenization
  • Emulsification
  • Dispersion
  • Mixing of fluids at high speed.
9
Sonicator
  • Mixing solutions
  • Accelerating the dissolution process
  • Removal of dissolved gases from the liquids.
10
Incubator Shaker
  • Ability to shake while maintaining optimal conditions for incubating microbes or DNA replications.
  • Used for growth of just about any kind of cell including bacterial cultures, tissue cultures, and yeast.
11
Centrifuge Research
(R24, Remi)
  • Useful way to separate particles using a centrifuge.
  • Separate various components of a fluid.
  • Employed for the separation of blood components from blood
12
Electrolyte Analyser (9180) (Roche)
  • Measurement of sodium, potassium, chloride, ionized calcium and lithium in blood.
  • Measuring the electrolytes in the human body.
13
Micropipette
  • Accurately and precisely transfer volumes of liquid in the microliter.
  • Administer biologically active substances.
  • Different length scales to study cell.
  • Accurately mixing, transferring, and applying a specific amount of dye to a cotton.
14
CO₂ Incubator
  • Provide sterile conditions for cultivation.
  • To maintain an optimal environment for cell growth.
  • To culture both bacterial and eukaryotic.
15
RT-PCR
(Thermofisher)
  • Most sensitive technique for mRNA detection and quantitation.
  • Detection of expressed genes, examination of transcript variants, and generation of cDNA templates.
16
Balance Digital CA-224 (CONTECH)

  • Unmatched accuracy and reliability.
17
ELISA Plate Analyser with Washer
(Robonik)
  • To ensure uniformity.
  • Detecting and quantifying soluble substances such as peptides, proteins, antibodies, and hormones.
18
UV spectrophotometer
  • Determination of CSF glutamate.
  • Qualitative analysis through spectrophotometric.
  • To analyse the level of compounds that are present in the medicine.